What method is used for mtDNA analysis?

Our mtDNA tests using DNA sequencing to analyze your mtDNA. Different regions of the mtDNA genome can be sequenced - just the HVR1 region, both hypervariable regions (HVR1 and HVR2), or the complete mitochondrial genome (HVR1, HVR2 and the coding region).

The entire DNA sequences for regions tested are provided to you in your mtDNA test report. Your mtDNA sequencing results are compared to a reference sequence called the “rCRS” (revised Cambridge Reference Sequence), and all of the positions within your mtDNA, which differ from rCRS are listed in your report.